Tuesday, 30 August 2016

New Solutions to Support a Pharmaceutical Value Chain that is in Flux | Len Mistretta

Time to market continues to be crucial. Developing processes that can be up and running quickly, enable fast changeovers, and reformulation as needed, can make the difference between success and failure in this fast-paced market.


Contract manufacturing can provide an effective approach to get production running quickly. The pharmaceutical industry has witnessed a shift from a vertically integrated business model to a network of suppliers. Contract manufacturing has evolved as one of the integral components of the pharmaceutical supply chain. The current marketplace has numerous established and emerging companies that can manufacture new products, offering a diverse collection of services. The scale of operation varies from manufacturing for clinical trials to full production. Contract manufacturing includes active pharmaceutical ingredient and finished dosage forms manufacturing. Contract manufacturing can also encompass packaging.

Another trend is the emergence of single-use disposable manufacturing. It is easy to imagine single use for filters or tubing systems but, today, even buffer containers and bioreactors are single use. Entire disposable facilities are also possible today at a fraction of the cost of traditional stainless steel manufacturing facilities. Manufacturing production that has to be up and running quickly, such as for a vaccine for a pandemic, often uses disposables.
China, India and other countries are rapidly developing domestic pharmaceutical, bio pharmaceutical, and generic drug industries. Due to increasing cost pressure and increased local demand, global pharmaceutical companies are locating production to emerging markets. Read More.....

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